Organic Synthesis by Taber Douglass;

Author:Taber, Douglass;
Language: eng
Format: epub
ISBN: 0199764549
Publisher: Oxford University Press, USA
Published: 2014-04-11T19:02:03+00:00

Professor Hartwig has also (Organic Lett. 2008, 10, 1545, 1549) optimized conditions for the Pd-catalyzed arylation of ester enolates such as 19. Gang Zhou of Schering-Plough, Kenilworth, NJ has developed (Organic Lett. 2008, 10, 2517) a related transformation, the arylation of deprotonated sulfonamides. Peter Somfai of the Royal Institute of Technology, Stockholm has established (Angew. Chem. Int. Ed. 2008, 47, 1907) a complementary procedure, base-mediated elimination of t-butoxide from 24, followed by 1,2-addition of an aryl or heteroaryl Grignard reagent.

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